IL-6 Variants in Ischemic Stroke

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IL-6 Variants in Ischemic Stroke

published from 2007 onward [7]. On the other hand, the results cited in the article appear to have been muddled. Thus, a study by Flex et al. [8] refers to an entirely different phenotype of peripheral artery occlu-sive disease (only 22 patients actually also had a history of stroke). Assuming that the authors had intended to refer to another study by the same author [9] , we face the obvious o...

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dysphagia in acute ischemic stroke

Introduction: Swallowing dysfunction complicates acute strokes in 25-32% of cases and directly affects patientschr('39') prognosis and recovery. Dysphagia complicates the course of acute strokes through its potential of the development of chest infection, nutritional problems, and dehydration.  Dysphagia is also an independent predictor of respiratory morbidity and mortality in acute stroke. In...

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Common mitochondrial sequence variants in ischemic stroke.

OBJECTIVE Rare mitochondrial mutations cause neurologic disease, including ischemic stroke and MRI white matter changes. We investigated whether common mitochondrial genetic variants influence risk of sporadic ischemic stroke and, in patients with stroke, the volume of white matter hyperintensity (WMHV). METHODS In this multicenter, mitochondrial genome-wide association study (GWAS), 2284 isc...

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NOTCH3 Variants and Risk of Ischemic Stroke

BACKGROUND Mutations within the NOTCH3 gene cause cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). CADASIL mutations appear to be restricted to the first twenty-four exons, resulting in the gain or loss of a cysteine amino acid. The role of other exonic NOTCH3 variation not involving cysteine residues and mutations in exons 25-33 in ischemic ...

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Gene Variants Associated With Ischemic Stroke

Background and Purpose—The purpose of this study was to determine whether 74 single nucleotide polymorphisms (SNPs), which had been associated with coronary heart disease, are associated with incident ischemic stroke. Methods—Based on antecedent studies of coronary heart disease, we prespecified the risk allele for each of the 74 SNPs. We used Cox proportional hazards models that adjusted for t...

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ژورنال

عنوان ژورنال: Annals of Neurosciences

سال: 2016

ISSN: 0972-7531,0976-3260

DOI: 10.1159/000443558